Women’s Mental Health

Journal Article Annotations
2021, 3rd Quarter

Women’s Mental Health

Annotations by Liliya Gershengoren, MD, MPH
September, 2021

  1. Suicidal Risk in Women with Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review and Meta-Analysis.

PUBLICATION #1 — Women’s Mental Health

Suicidal Risk in Women with Premenstrual Syndrome and Premenstrual Dysphoric Disorder: A Systematic Review and Meta-Analysis.
Divya Prasad, Bianca Wollenhaupt-Aguiar, Katrina N Kidd, Taiane de Azevedo Cardoso, Benicio N Frey

Annotation

The finding:
Results from this meta-analysis demonstrate an association between PMDD and suicidality. Women with PMDD are at higher risk of suicide attempts and ideation by almost seven- and fourfold, respectively. Furthermore, PMS and premenstrual symptoms are risk factors for suicidal ideation but not suicide attempts.

Strength and weaknesses:
There is a paucity of research on PMDD and suicidality. This meta-analysis attempts to quantitatively confirm results of prior studies describing an association of PMDD with suicidal thoughts, ideation, plans, and attempts. The limitation of this study includes its inclusion of studies written in English and Spanish only. In addition, most studies described a cross-sectional design that limits the ability to draw causal relationships between PMDD, PMS, and suicidality.

Relevance:
C-L psychiatrists working in OB/GYN or general hospital settings often encounter patients with suicidal ideation or a recent suicide attempt. Increased awareness of premenstrual disturbances in these patients will further help to tailor treatment from a multidisciplinary perspective.